Digoxin Monitoring Guidelines. Loading doses of digoxin should be halved in the elderly and in those with renal impairment (creatinine clearance.
Summary And Comparison Of Clinical Guidelines Relating To Renal Download Table from www.researchgate.net
PDF fileAdapted with permission from a guideline by Dorset County Hospital NHS Trust (Author Christine Dodd Clinical Pharmacy Manager) Review Date September 2016 Digoxin – Loading Dose Guide (Adults) Digoxin is indicated in the management of chronic cardiac failure The.
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Digoxin levels are reported in µg/L To convert from µg/L to nmol/L multiply by 128 Approximately 90% adult patients with proven digoxin toxicity have serum digoxin levels greater than 20 µg/L if the sample was collected at least 6 hours after the last dose Target range in heart failure is 05 to10 µg/L Target range in AF is 05 20 ug/L.
Digoxin Prescribing information Atrial fibrillation
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Digoxin Time to steady state 7–10 days Sampling time and target range Sample 6–24 hours after dose Target range 05–2micrograms/L 05–1micrograms/L (in heart failure) Comment Dose depends on renal function Digoxin dosing advice in ‘Drugs for atrial fibrillation’ section refers to loading doses and initial maintenance doses in renal impairment.
Summary And Comparison Of Clinical Guidelines Relating To Renal Download Table
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PDF fileIn urgent cases Dilute 500mcg (2ml) of digoxin with at least 8ml of sodium chloride 09% or glucose 5% (total volume = 10ml) and give by slow intravenous injection over 1020 minutes The age serum potassium levels and renal function of the patient should also be taken into account when dosing digoxin.
