Pf 500 Pelet. In vitrotranscribed messenger RNAbased therapeutics represent a relatively novel and highly efficient class of drugs Several recently published studies emphasize the potential efficacy of mRNA vaccines in treating different types of malignant and infectious diseases where conventional vaccine strategies and platforms fail to elicit protective immune responses.
Tam HH Melo MB Kang M Pelet JM Ruda VM Foley MH et al Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination Proc Natl Acad Sci U S A 2016 113E6639–E6648 doi 101073/pnas1606050113 [PMC free article] [Google Scholar].
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